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Showing posts from March, 2020

TAFINLAR (dabrafenib)

TAFINLAR (dabrafenib) capsules, in combination with MEKINIST® (Tramatinib) tablets, are indicated: For the treatment of patients with involuntary or metastatic melanoma with BRF V600E or V600K mutations detected by FAR-approved testing For adjuvant treatment of patients with melanoma with BRF V600E or V600K mutations, as revealed by FDA-approved testing, and lymph node (s) involvement after complete resection. For the treatment of metastatic non-small cell lung cancer (NSCLC) patients with Brett V600E mutation as revealed by FAR-approved testing Limitations of use: TAFINLAR is not indicated for the treatment of patients with wild-type BRF melanoma or wild-type BRF NSCLC. Important safety information New primary malaise, dermal and non-dermal. Perform dermatologic evaluation every 2 months before initiation of therapy, and up to 6 months after discontinuation of the combination. Closely monitor patients for signs or symptoms of nonfatal malformations. Permanently discontinue TAFINLAR

Abatacept (Orencia)

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Abatacept (Orencia) is often prescribed after failure of an anti-rheumatic agent (DMARD), such as methotrexate. But it can be used as first-line therapy. Ebetasip is used to reduce inflammatory symptoms such as swelling, pain, and stiffness. In the long term, it is expected to prevent joint deformity, therefore helping to maintain range of motion. It is often used in patients with moderate to severe rheumatoid arthritis who have not responded to one or more DMARDs, such as methotrexate, or other biologic drugs. DMARDs are usually tried first. Abatacept may be used alone or in combination with DMARDs, which makes it more potent, but not with other biologic drugs (such as TNF inhibitors). Its use in other diseases is still being studied. Unlike some other biologic drugs, abetacept does not block anti-inflammatory proteins such as TNF-alpha antagonists. Abatacept attaches to the surface of inflammatory cells and blocks communication between these cells. By blocking this communicatio

MEKINIST

TAFINLAR® (dabrafenib) capsules, in combination with MEKINIST® (Tramatinib) tablets, are indicated: For the treatment of patients with involuntary or metastatic melanoma with BRF V600E or V600K mutations detected by FAR-approved testing For adjuvant treatment of patients with melanoma with BRF V600E or V600K mutations, as revealed by FDA-approved testing, and lymph node (s) involvement after complete resection. For the treatment of metastatic non-small cell lung cancer (NSCLC) patients with Brett V600E mutation as revealed by FAR-approved testing Limitations of use: TAFINLAR is not indicated for the treatment of patients with wild-type BRF melanoma or wild-type BRF NSCLC. Important safety information New primary malaise, dermal and non-dermal. Perform dermatologic evaluation every 2 months before initiation of therapy, and up to 6 months after discontinuation of the combination. Closely monitor patients for signs or symptoms of nonfatal malformations. Permanently discontinue TAFINLAR

Efractory Acute Myeloid Leukemia (AML)

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Indicated for refractory / refractory acute myeloid leukemia (AML) with an isocitrate dehydrogenase-2 (IDH2) mutation as revealed by FDA-approved testing 100 mg PO qDay with or without food until disease progression or unacceptable toxicity In patients without disease progression or unacceptable toxicity, treat to6 months to allow time for clinical response Dose modification Hallucination syndrome If discrimination syndrome is suspected, administer systemic corticosteroids; Initiate hemodynamic monitoring Intercadibib dosing if pulmonary symptoms (eg, intubation / ventilator support) and / or renal dysfunction persist for corticosteroid initiation after> 48 hours Reset Encenidib when signs / symptoms improve (grade 2 (mild-moderate)) Non-infectious leukocytosis (WBC> 30,000 mcL) In accordance with standard institutional guidelines, initiate hydroxyurea Intercadibib dose if there is no improvement of leukocytosis after the onset of hydrosaurea Resume enasidenib 1

How To Support Someone You Know Suffering from Cancer

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Supporting a patient who is suffering from cancer can be an uphill job. Many people want to help in these but they don't know how to do it. In this article, we have suggested you some ways through which you can show your care.  A patient suffers from cancer pass through a lot of emotions. Negative feelings containing depression and fear move in a patient's mind. No one can understand the emotion and physical disorder of the person. With a loss of words and fear to hurt the emotions of a person. Thus, being a well-wisher, you will definitely want to meet and show him you care. For a cancer patient, anti-cancer medicines in India is very important. Here are some ideas that will support someone with this disease.  Listen to him carefully   Every cancer patient will be the unique experience, so listen whatever he has to say as it will support him the most. Knowing about his fears will make you uncomfortable and expressing emotions will make him feel comfortab