What is ELAPRASE (IDURSULFASE) and what is it used for?

ELAPRASE (idursulfase) is an IV infusion used to treat some of the symptoms of a genetic condition called Hunter’s syndrome, also called mucopolysaccharidosis (MYOO-koe-pol-ee-SAK-a-rye-DOE-sis). Idursulfase contains a natural enzyme that some people lack because of a genetic disorder. Elaprase helps replace this missing enzyme.

ELAPRASE is a prescription medicine for patients with Hunter syndrome

ELAPRASE has been shown to improve walking ability in patients 5 yrs and older.

In patients 16 months to 5 yrs old, ELAPRASE did not show improvement in disease-related symptoms or long term clinical result; however, treatment with ELAPRASE has reduced spleen size similarly to patients 5 yrs and older.

It is not known if ELAPRASE is safe and effective in children under 16 months old.

Hunter syndrome occurs when the body is unable to produce an enzyme called iduronate-2-sulfatase (I2S), which is responsible for breaking down GAGs. The buildup of GAGs in the body can cause a range of symptoms, including developmental delays, joint stiffness, heart problems, and respiratory issues.



ELAPRASE works by providing the body with a synthetic version of the missing I2S enzyme. It is administered through intravenous infusion every week, and treatment is typically lifelong.

ELAPRASE has been shown to improve a variety of symptoms in patients with Hunter syndrome, including joint mobility, respiratory function, and overall quality of life. However, it is important to note that ELAPRASE does not cure Hunter syndrome and cannot reverse any damage that has already occurred.

Like all medications, ELAPRASE can cause side effects. Common side effects of ELAPRASE include headache, fever, and respiratory infections. More serious side effects are rare, but can include severe allergic reactions or anaphylaxis.

Overall, ELAPRASE is an important medication for patients with Hunter syndrome, as it can help to improve their quality of life and potentially slow the progression of the disease.

Location: New Delhi, Delhi 110038, India

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